You should start from Est Gearen and go on with Sheridan village and so on.
As for the relevant to the story are a few exceptions (hidden library,april quest in amethyst cave) but in the rest i dont think are athores , that is if you are refering relevant to the main story.
You can open those doors by pressing some pillars for you to press them you will need surf i think, rock smash ,strenght (maybe), rock climb and you need to
go to wispy path and you.ll see where you need to use rock climb there
but if we put all the things she been trough like being chased by team xen having her father killed in front of her also nim now her best friend is frozen this are some truma cases over here.
But also as i said don.t take it serious is just something i came up with
Soooo.....
This thing came to me after watching some other people playing rejuvenation on youtube ......
anyways in the final scenes where venom is frozen melia just goes insane and this made me think that mabe in the end melia will die just because good characters like her when they go insane most of the time they die .
I know is just some random thought don.t take it serious this is my random thinking =))
ok from what i can tell either you have your save file corupted wich you should replace with an older one
or
wich version of the game are you using because if your using v9 and try to load older versions won,t work
and
the last think you can do patch your game
either ways if those don.t work try talking with jan
good luck i hope you can resolve this