Nope. Sceptile doesn't get U-turn. But according to Godot movepool expansion's a possibility. If it does end up with access to U-turn then yeah, this'll definitely be a thing. Otherwise I don't see much potential in a lead. Being weak to U-turn and frail is a bad quality in a lead.
Overall I don't see Sceptile moving much because of this. It'll definitely make it to UU and it'll appear on OU teams that need a Rotom-W check bad enough to sacrifice their mega slot for it.
Unfortunately I see a lot of Sceptile's mega points going into both attacking stats. This could make for a great mixed attacker with leaf storm, a la overheat Infernape, but most people will likely run fully physical or fully special sets.
I could be wrong though. It's all speculation at this point.